A cross-sectional study was conducted to capture undergraduate nursing students’ digital health literacy and attitudes toward telehealth use in practice at a single point in time. This study was reported according to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement guidelines (Checklist 1).

This study focused on students enrolled in a Bachelor of Nursing program within a selected university in western Saudi Arabia. In this selected program, telehealth was introduced theoretically to nursing students in many courses; however, limited practical opportunities were available in clinical settings. A convenience sampling method was applied to recruit the participants, which included distribution of invites through social media platforms, emails, and announcements sent through the university’s learning management system. To prevent duplicate responses, only 1 submission per device was allowed.

The inclusion criteria for the study were current nursing students in their second year to internship year. First-year students were excluded because they had not yet progressed into the specialized nursing curriculum and had limited exposure to clinical courses, nursing informatics, or telehealth-related learning experiences. Therefore, only second-year, third-year, fourth-year, and internship students were included to ensure that participants had sufficient academic and clinical exposure to meaningfully evaluate digital health literacy and attitudes toward telehealth use in practice. Licensed or registered nurses enrolled in bridging or postlicensure programs were excluded because prior professional experience may influence digital health literacy and attitudes toward telehealth use in practice independently of undergraduate nursing education.

The data were collected from November 2025 to January 2026. During this research period, 440 female and 223 male nursing students were enrolled in the Bachelor of Nursing program. The targeted sample size was 244, which met the required sample size, with a 95% CI and 5% margin of error.

The survey consisted of 3 sections: part 1 asked about demographic data, while the second and third parts used 2 scales adopted from previously published and publicly accessible studies [18,19]. The first part of the survey collected demographic data such as sex, age, and academic year (second, third, fourth, or internship). Four questions inquired whether students had attended workshops or lectures related to telehealth, had taken nursing informatics courses, understood the definition of telehealth, and had applied telehealth in clinical placements.

The second part of the survey assessed digital health literacy using the Digital Health Care Literacy Scale (DHLS), with 3 items adopted from a previously published and publicly accessible study [18]. The scale exploratory factor analysis demonstrated good psychometric properties, with Cronbach α of 0.90 and 78% explained variance, supporting the scale’s validity and reliability [18]. The responses were measured using a 5-point Likert scale ranging from strongly disagree to strongly agree.

The third part of the survey assessed the students’ attitudes toward telehealth in practice using the 19-item Nurses’ Attitudes Toward Use of a Telehealth Scale (NATUTS), which was obtained from a previously published and publicly accessible study [19]. NATUTS measured 3 factors: satisfaction, rejection, and development. The instrument demonstrated strong psychometric properties, with Cronbach α values ranging from 0.86 to 0.93 and a total explained variance of 64.4%, supporting its validity and reliability for assessing attitudes toward telehealth [19]. For descriptive interpretations purposes, the items were conceptually grouped under 4 domains, namely perceived benefits, professional integration and reliability, negative emotions and resistance, and engagement and self-development. Responses were recorded using a 5-point Likert scale ranging from strongly disagree to strongly agree.

The survey was administered in English because English is the language of nursing instruction at the study institution, and translation was therefore not needed. The survey was checked for face and content validity to assess its clarity and relevancy to the study objective before distribution. It was sent to 3 experts in nursing education and digital health for feedback. A pilot test was conducted with 10 nursing students to evaluate clarity, readability, and completion time. No modifications were required based on their feedback. Pilot participants were excluded from the final analysis.

The 3 DHLS items were adopted to assess the level of digital health literacy of the students. Each item was rated using the 5-point Likert scale, ranging from 1 (strongly disagree) to 5 (strongly agree). The 3 items were rated accordingly, and the total DHLS scores ranged from 3 to 15. The digital health literacy score was classified accordingly: 3 to 7 (low), 8 to 11 (moderate), and 12 to 15 (high). The total NATUTS score was calculated by adding up all 19 items after negatively worded items were reverse-coded to investigate predictors of positive attitudes toward telehealth. The total NATUTS scores ranged from 19 to 95. Higher scores indicated more positive attitudes toward telehealth use in practice. The sample mean score was used as a cutoff to dichotomize the overall attitude score. Mean score dichotomization has been used to facilitate interpretation of logistic regression outcomes when no established cutoff exists. Values below the mean were classified as negative attitudes, and scores equal to or above the mean were classified as positive attitudes. The multivariable logistic regression model was then fitted with the dichotomized variable.

SPSS (version 28; IBM Corp) was used to perform all statistical analyses. Descriptive statistics were adopted to classify the nursing students’ educational background, level of digital health literacy, sociodemographic attributes, and attitude toward telehealth use in practice. Frequencies and percentages denote the categorical variables, and means and SDs denote the continuous variables.

To examine factors associated with positive attitudes toward telehealth use in practice, multivariable logistic regression analysis was performed. Digital health literacy score, age, sex, academic year, exposure to telehealth education, completion of a nursing informatics course, and telehealth use during clinical placement were entered as independent variables in the model. Adjusted odds ratios (AORs) with 95% CIs were calculated. A P value of <.05 was considered statistically significant.

The study adhered to ethical research standards and received approval by a relevant institutional review board of Umm Al-Qura University (receipt number HAPO-02-K-021-2025-5-2785). A statement at the beginning of the survey informed participants of the study’s objectives, processes, possible benefits, and any related risks. It explained that participants’ identities would remain anonymized and protected.

Participants provided consent by completing and submitting the survey anonymously. There were no significant risks, and the only cost to the participants was the time taken to complete the survey. Participation was voluntary, and responses were collected anonymously. No financial compensation or incentives were provided to participants for taking part in the study.

The purpose of this study was to examine the relationship between digital health literacy and attitudes toward telehealth use in practice among nursing students. The findings demonstrated that high digital health literacy was significantly associated with positive attitudes toward telehealth use in practice. Students with higher digital health literacy were significantly more likely to perceive telehealth as beneficial, reliable, and relevant for nursing practice.

Most of the nursing students demonstrated a high level of digital health literacy. This result aligns with previous studies that found moderate to high digital health literacy among nursing and health sciences students [20,21]. However, the findings should be interpreted with caution. Although students may possess the ability to access and use digital health information, this does not necessarily indicate preparedness to apply telehealth in complex clinical situations. Previous studies have shown that nursing students often experience difficulties in critically evaluating online health information and in applying digital knowledge in clinical decision-making [20,21]. Thus, possessing digital health literacy skills alone may be insufficient without practical telehealth training and supervised clinical application.

Most of the students stated that telehealth decreases workload, improves the quality of life of patients, and plays a critical role in nursing practice. These results are consistent with those of previous studies demonstrating that nursing students perceive telehealth as beneficial to health care accessibility, efficacy, and communication [19,22]. Positive attitudes toward telehealth use in practice may reflect nursing students’ increasing exposure to digital technologies in both educational and health care settings. These attitudes may also be influenced by the rapid expansion of telehealth services following the COVID-19 pandemic [6,20]. Thus, students may perceive telehealth as consistent with contemporary nursing roles which require digital communication and remote patient monitoring [4,22].

Despite the reported positive attitudes, some students exhibited negative feelings such as reluctance and nervousness. These findings are important because they show that positive attitudes can sometimes coexist with discomfort, limited confidence, or perceived external pressure to use digital technologies. This may indicate that some students accept telehealth while still lacking confidence in their practical ability to use it efficiently and effectively. Such findings align with those of previous research, where the nursing students were hesitant due to reliability concerns and insufficient practical exposure [12,23]. These findings suggest that telehealth education should include hands-on simulation and supervised practice experiences to improve confidence and reduce resistance.

The presence of negative emotions toward telehealth use in practice may reflect limitations of current nursing education strategies. Although many students attended telehealth workshops or completed informatics-related courses, these experiences did not lead to more positive attitudes toward telehealth use in practice. This finding suggests that current educational strategies may emphasize theoretical knowledge more than practical competency. Short workshops or isolated informatics courses may increase awareness of telehealth without sufficiently improving students’ confidence, communication skills, or ability to integrate telehealth into patient care [23]. Subsequently, students may recognize the importance of telehealth while experiencing anxiety or resistance to its practical implementation.

Digital health literacy independently predicted students’ attitudes toward telehealth use in practice even after controlling for demographic and educational variables. This finding suggests that digital health literacy is not only a technical skill but also a determinant of technology acceptance in health care settings. Students who are confident in using digital tools may perceive telehealth systems as easier to use and thus more useful in clinical care. These results align with the Technology Acceptance Model, which suggests that individuals with higher perceived competence in technology are more likely to adopt digital innovations in practice [14,15]. However, students with lower literacy levels may experience uncertainty and resistance due to difficulties navigating digital health care environments. These findings suggest that digital competencies play a critical role in shaping students’ readiness to adopt telehealth technologies in future clinical practice. As telehealth becomes increasingly integrated into health care systems globally, digital health literacy may represent an essential professional competency for future nurses [4]. Therefore, improving digital health literacy may help not only to develop technical competence but also to reduce anxiety and strengthen professional acceptance of telehealth technologies.

The study statistically found that male students were less likely to report positive attitudes toward telehealth use in practice than female students. Although evidence regarding sex differences in attitudes toward telehealth among nursing students remains limited, this result may be related to communication preferences, engagement with patient-centered care, or attitudes toward health care technologies. However, this result should be interpreted cautiously given the lack of literature available and the potential influence of cultural and educational factors. Additional research is needed to better understand the reasons underlying these differences.

Overall, the results imply that telehealth education in nursing programs needs to be further enhanced beyond theoretical instruction. While students generally demonstrated positive attitudes and high digital health literacy, the persistence of nervousness, reluctance, and feelings of obligation indicates gaps between knowledge and practical readiness. Nursing curricula may benefit from integrating experiential telehealth learning activities such as simulations, virtual consultations, case-based learning, and supervised clinical telehealth experiences. These approaches may help students develop greater confidence, reduce resistance, and improve their ability to apply telehealth competently in real health care settings.

To summarize, digital health knowledge reflects understanding, whereas digital health literacy reflects the capacity to apply that understanding in practice. This study contributes to existing evidence that digital health literacy plays an important role in technical competence and is positively associated with students’ attitudes toward telehealth use in practice. Nursing education courses need to strengthen digital competencies to reduce resistance and promote more positive perceptions of telehealth within nursing. As telehealth becomes integrated into health care systems worldwide, preparing digitally competent nursing graduates is critical to future workforce readiness.

The cross-sectional design and single-educational setting of this study make it difficult to draw conclusions about the causal relationships between students’ attitudes toward telehealth use in practice and their level of digital health literacy. It was not possible to ascertain whether exposure to telehealth education results in long-lasting changes in attitudes or abilities because the data were gathered all at once. Additionally, the results are less applicable to other nursing programs with distinct curricula, resources, or student characteristics when the study is limited to a single institution. Consequently, findings should be interpreted cautiously, as they might not be generalizable to the broader population of undergraduate nursing students because of potential self-reported bias.

The findings of this study demonstrate that nursing students have high levels of digital health literacy. In addition, most of the students exhibit positive attitudes toward telehealth use in practice, particularly pertaining to patient care delivery, decreasing workload, and professional integration. The significant finding was the association between higher digital health literacy levels and positive attitudes toward telehealth use in practice. These findings suggest a potential need to strengthen digital health content within nursing curricula to strengthen nurses’ digital skills through formal training and continuous professional development.

Educators and clinical leaders can modify training strategies to meet the needs of specific groups. This targeted approach may reduce disparities in digital health and telehealth competencies across the clinical workforce. Offering workshops or informal learning experiences does not guarantee improved competency, so such clinical training should include skills that support telehealth use. Integrating structured, evidence-based digital health literacy curricula into clinical training may ensure that future health care providers develop their competency as technologies evolve.